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A duodenal switch procedure is also known as biliopancreatic diversion with a duodenal switch, or BPD-DS. This procedure is more complex than other types of weight loss surgery, and it is less commonly performed.
A duodenal switch involves two surgical procedures.
This type of surgery may allow more weight loss, but it is also the most likely to cause surgery-related problems and vitamin or mineral deficiencies. For that reason, this procedure is generally recommended for people with a body mass index (BMI) greater than 50.
The single-anastomosis duodenal switch, also called stomach intestinal pylorus sparing surgery (SIPS), or the single loop DS, is very similar to the standard duodenal switch operation, except that the small intestine is only transected at one point instead of two.
This procedure may be performed as a single operation in some patients.
The gastric sleeve is created as a primary operation to achieve some weight loss and health improvement. Then typically a year after laparoscopic sleeve gastrectomy, patients who still have a BMI > 40, significant medical comorbidities and those who need an additional metabolic push, will proceed to the second laparoscopic operation to complete the SADI-S procedure.
The SADI-S procedure is performed after the lap sleeve gastrectomy by bypassing roughly half of the upper small intestine, resulting in a moderate decrease in calorie absorption and powerful gut chemistry changes to effect metabolism. Weight loss is achieved through restriction of food consumption, metabolic change and some malabsorption, which results in very good long-term weight loss maintenance.
The SADI-S procedure will re-route the intestines so that calorie absorption is moderately reduced.
The duodenum (the first section of the small intestine) is transected after the pylorus. Rather than transecting the lower intestines (as is done with the standard duodenal switch), the surgeon simply attaches the small intestine at a point approximately 8-10 feet or 250-300 cm from the colon to the duodenal stump just beyond the pyloric valve. This creates a loop that diverts the food stream from the top half of the small intestines.
The top half of the intestine now carries just digestive juices (bile and pancreatic juices), and is called the bilio-pancreatic limb (BPL). The last segment of the intestine where the food and digestive juices mix is referred to as the common channel (CC).
Absorption of nutrients and calories is determined by the length of the common channel, so a shorter channel helps decrease the chance of weight regain by decreasing calorie absorption.
One reason that good long-term weight loss has been reported with the duodenal switch with single anastomosis is likely due to a dramatic decrease in the appetite-producing hormone known as ghrelin. The tissue that produces the hormone is almost completely removed with the outer portion of the stomach during the sleeve gastrectomy operation.
Patients typically report a significant decrease in hunger and food consumption after this first stage operation. In addition, re-routing the intestines helps bring food to the lowest portion of the small intestines earlier than usual which releases important appetite-suppressing hormones such as polypeptideYY (PYY) and glucagon-like peptide 1 (GLP1). This may explain the superior weight loss, weight maintenance and diabetes resolution associated with this surgery.
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